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Pemphigoid - Symptoms, Causes and Prevention

Pemphigoid in Urdu

یہ ایک بہت کم پایئ جنے والی آٹو امیون بیماری ہے جو کہ کسی بھی عمر اور جنس کے افراد کو متاثر کر سکتی ہے۔ یہ بیماری مدافعتی نظام کی ناقص کارکردگی کی وجہ سامنے آتی ہے۔ اس کی علامات میں ٹانگوں، بازئوں اور پیٹ پر خاعشیں اور چھالے بننا شامل ہیں۔

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Summary about Pemphigoid in English

Pemphigoid is a rare autoimmune disease that can strike anyone at any age, including children, but most commonly affects the elderly. Pemphigoid is a skin rash and blistering condition caused by an immune system malfunction. It affects the arms, legs, and abdomen. Pemphigoid has no cure, but there are several treatment options available.

Symptoms of Pemphigoid

Blisters on the arms, legs, abdomen and mucous membranes are the most common symptom of pemphigoid. Itching and hives are also common. Regardless of where they form on your body, blisters have several characteristics:

  • a red rash appears before the blisters
  • Large blisters that are filled with fluid, which is usually clear, but may contain blood as well
  • thick blisters that do not rupture easily
  • the skin around those blisters might look normal or slightly red or dark
  • ruptured blisters are generally sensitive and painful

Causes of Pemphigoid

Pemphigoid is an autoimmune disease affecting the skin. It is more common in people who have other autoimmune disorders. It's common in the elderly than in any other age group, with women slightly outnumbering men. It has no specific cause in many cases. However, in some cases, it could be caused by:

  • certain medications
  • ultraviolet light therapy
  • radiation therapy

Treatment

Although pemphigoid cannot be cured, treatments are usually very effective in alleviating symptoms.

  • The first treatment your doctor will likely prescribe is corticosteroids, either in pill or topical form. These medications can help heal blisters and relieve itching by reducing inflammation. However, corticosteroids may have serious side effects, especially when used for a long time; your doctor will taper you off of them once the blistering has gone away.
  • Another treatment option is to take an immune-suppressing medication, which is often used in conjunction with corticosteroids. Immunosuppressive medications can help, but they can also put you at risk for other infections. To reduce inflammation and infection, antibiotics such as tetracycline may be prescribed.

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