Image of Metodine DF Suspension

Metodine DF Suspension Uses

Manufacturer:- The Searle Company Ltd.
Generic Name:- Diloxanide Furoate + Metronidazole
Formula:- Diloxanide Furoate + Metronidazole...250mg/200mg per 5ml
Drug Class:- Luminal amoebicide and nitroimidazole antiprotozoal combination
Medicinal Form:- Suspension

About Metodine DF Suspension

Metodine DF Suspension uses include the treatment of intestinal amoebiasis and amoebic dysentery, and clearing amoeba cysts from the bowel. It contains metronidazole, which kills amoeba by damaging their genetic material, and diloxanide furoate, which works inside the bowel to clear the amoeba cysts. Use it only under medical supervision because the dose depends on age and body weight, and alcohol must be avoided during treatment.

Metodine DF Suspension Uses

Your doctor might give you Metodine DF Suspension for:

  • Intestinal amoebiasis
  • Amoebic dysentery
  • Passing amoeba cysts in the stool without symptoms
  • Amoebic liver abscess, along with other treatment

Metodine DF Suspension Dosage and Administration

Always follow your doctor's instructions exactly.

Adult Dosage:

  • Each 5ml contains 250mg diloxanide furoate and 200mg metronidazole
  • Usual adult dose of diloxanide furoate: 500mg three times daily for 10 days
  • Usual adult dose of metronidazole for amoebiasis: 400mg to 800mg three times daily for 5 to 10 days
  • 10ml three times daily gives 500mg diloxanide furoate and 400mg metronidazole per dose
  • Your doctor will set the exact dose and length of treatment

Children Dosage:

  • Over 12 years: same as adult dosage
  • Diloxanide furoate up to 12 years: 20mg per kg per day in 3 divided doses for 10 days, not more than 1.5g a day
  • Metronidazole for amoebiasis: 35mg to 50mg per kg per day in 3 divided doses for 5 to 10 days, not more than 2400mg a day
  • The doctor will work out the ml dose from the child's weight

How to Take:

  • Shake the bottle well before each dose.
  • Measure the dose with the measuring cup or syringe, not a kitchen spoon.
  • Take the doses at evenly spaced times each day.
  • Complete the full course even if you feel better.
  • Do not drink alcohol during treatment and for at least 48 hours after the last dose.

Metodine DF Suspension Warnings

Don't use Metodine DF Suspension if you:

  • Are allergic to metronidazole, diloxanide furoate, or any ingredient
  • Are allergic to similar medicines such as tinidazole

Metodine DF Suspension Precautions

Talk with your doctor first if you:

  • Have liver disease
  • Have Cockayne syndrome
  • Have epilepsy or a nerve disease
  • Have a blood disorder
  • Are pregnant or breastfeeding
  • Take warfarin, lithium, disulfiram, busulfan, ciclosporin, or seizure medicines such as phenytoin or carbamazepine

Also, remember:

  • Avoid alcohol during treatment and for 48 hours after it
  • It may turn your urine dark
  • It may cause dizziness or drowsiness, so take care when driving
  • Your doctor may check your blood count if treatment lasts more than 10 days
  • Stop it and see a doctor if you get numbness or tingling in the hands or feet

Metodine DF Suspension Side Effects

Metodine DF Suspension is generally well tolerated, but some people may experience side effects.

  • Flatulence
  • Nausea
  • Stomach cramps
  • Loss of appetite
  • Diarrhoea
  • Metallic taste or furred tongue
  • Headache
  • Dark urine

Serious side effects:

  • Severe allergic reaction with swelling of the face, lips, or throat
  • Hives
  • Severe skin rash with blisters or peeling
  • Fits, confusion, or hallucinations
  • Numbness or tingling in hands or feet
  • Yellowing of the skin or eyes
  • Severe stomach pain spreading to the back
  • Unexplained bruising, sore throat, or infections

Storage Instructions

  • Store below 30°C
  • Protect from direct sunlight and moisture
  • Keep out of reach of children
  • Do not use after expiry date

Packaging and Quantity

Metodine DF Suspension is available as:

  • 250mg/200mg per 5ml: Pack of 90ml suspension

Prescription Requirement

It is a prescription-only medicine due to its potential side effects and to prevent misuse.

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Frequently Asked Questions about Metodine DF Suspension

Metodine DF Suspension is used to treat intestinal amoebiasis and amoebic dysentery, and to clear amoeba cysts from the bowel in people who pass cysts without symptoms.
No. The metronidazole in Metodine DF can react with alcohol and cause flushing, vomiting, and a fast heartbeat. Avoid alcohol during treatment and for at least 48 hours after the last dose.
Metronidazole kills amoeba that invade the gut wall and other tissues. Diloxanide furoate works inside the bowel to clear the cysts that can stay behind and cause the infection to return. Together they treat both forms.
The price of Metodine DF Suspension 250mg/200mg per 5ml 90ml is Rs. 150 in Pakistan. The price may vary slightly between pharmacies.
میٹوڈین ڈی ایف سسپنشن آنتوں میں امیبا کے انفیکشن، امیبک پیچش اور پاخانے میں امیبا کے سسٹ ختم کرنے کے لیے استعمال ہوتا ہے۔

Disclaimer

The Marham platform strives to offer expert-reviewed information, which includes error elimination for all its consumers. Patients should always consult experts for medical advice instead of relying on this information. The information available on this page is for general information purposes only. Always seek medical advice from your doctor before using medicine or expressing health-related worries.

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