I am a bipolar patient and i had severe depression n hypomania which was controllable when i take any mood stabiliser.my depression was very stubborn and i have tried all antidepressants in market i was on lurisa butrin brintellix and sensival which worked well for me my cognition was outstanding after taking these four medicines and i felt completely normal but unfortunately i skipped these medicines i started taking again these medicines and its now 22 days i am on these medicines but they r not working so far.i feel when i skipped them they developed tolerance.what should i have to do now i am very upset i found this combo after 5 r 6 years and m sorrowful.kindly help me.