کشنگ سنڈروم ایک نایاب ہارمونی بیماری ہے جس میں جسم میں کارٹیسول نامی ہارمون کی مقدار حد سے زیادہ بڑھ جاتی ہے۔ اس کی وجہ سے چہرہ گول اور سرخی مائل ہو جاتا ہے، پیٹ اور کندھوں پر چربی جمنے لگتی ہے، اور جلد پر نشانات نمودار ہو سکتے ہیں۔ یہ بیماری زیادہ تر طویل عرصے تک سٹیرائیڈ ادویات کے استعمال یا غدودوں میں رسولی کی وجہ سے ہوتی ہے۔ بروقت تشخیص اور علاج سے مریض معمول کی زندگی گزار سکتا ہے۔
Family Medicine, General Physician, Internal Medicine Specialist
MBBS , MCPS (Family Medicine)
General Physician, Internal Medicine Specialist
BSc, MBBS, PSIM,MD Medicine
Pulmonologist / Lung Specialist, General Physician, Diabetologist
MBBS, DTCD (T.B and Chest Diseases), MCPS (T.B and Chest Diseases), FCCP (USA)
Endocrinologist, Diabetologist
MBBS, FCPS (Medicine), Fellow in Endocrinology Diabetes and Metabolism
Internal Medicine Specialist, General Physician, Pulmonologist / Lung Specialist, Diabetologist, Family Medicine
MBBS, MD (Medicine), MD (Pulmonology), FACP (USA)
Internal Medicine Specialist, General Physician, Diabetologist, Family Medicine
MBBS, FCPS (Medicine), MRCP (Medicine)
Cushing syndrome meaning in Urdu is "کشنگ سنڈروم، یعنی جسم میں ہارمون کی زیادتی کا مرض". It is a rare hormonal condition that develops when the body has too much cortisol for a long time. Cortisol is a hormone that helps the body manage stress, blood pressure, and metabolism. When its level stays high, it causes many physical and emotional changes.
The most common cause is the long-term use of corticosteroid medicines for conditions like asthma, arthritis, and lupus. In other cases, a tumor on the pituitary or adrenal gland produces extra cortisol. The condition can affect anyone. However, it is most common in adults between 20 and 50 years of age. With treatment, most people recover well.
Cushing syndrome usually develops slowly. The most common signs include:
Seek a doctor's help if you notice:
Cushing syndrome happens when the body has too much cortisol. The main causes include:
You may be more likely to develop Cushing syndrome if you:
Cushing syndrome cannot always be prevented, however the risk can be reduced by:
Cushing syndrome is grouped based on what is causing the excess cortisol:
This is the most common form. It develops when a person takes high doses of corticosteroid medicines for a long time. Symptoms improve when the medicine is reduced under medical supervision.
This type happens when the body itself produces too much cortisol. It is usually caused by a tumor in the pituitary gland, adrenal gland, or somewhere else in the body.
This is a specific form of endogenous Cushing syndrome. It develops when a non-cancerous tumor in the pituitary gland releases extra ACTH, which makes the adrenal glands produce too much cortisol.
In this type, tumors outside the pituitary gland produce ACTH. These tumors are most commonly found in the lungs.
This form develops when a tumor in one of the adrenal glands makes too much cortisol directly, without involving ACTH.
Doctors use several tests to diagnose Cushing syndrome and find its cause:
Treatment depends on the cause of excess cortisol. The goal is to bring cortisol levels back to normal and treat related complications.
(Home remedies do not cure Cushing syndrome. They only support medical treatment.)
(All medicines must be taken under an endocrinologist's supervision.)
If not treated, Cushing syndrome can lead to serious problems:
Cushing syndrome needs careful diagnosis and long-term care. Marham helps you connect with trusted, verified, and experienced doctors who can guide you through testing and treatment. Book an appointment with the best endocrinologist through Marham today.
Marham shares expert-reviewed information to support your health journey. The information on this page is only to guide and inform you. For any personal advice, it’s always best to check with a medical professional.
The most common cause is the long-term use of high-dose corticosteroid medicines used to treat conditions like asthma, lupus, and rheumatoid arthritis. Tumors in the pituitary or adrenal glands are the next most common causes.
Yes, most cases can be cured or well controlled. If steroid medicines are the cause, slowly reducing them with a doctor's help usually fixes the problem. For tumor-related cases, surgery to remove the tumor offers the best chance of cure.
The face becomes round and full, frequently called a moon face. The skin on the face may look red and flushed. Some people also notice a fatty hump on the upper back between the shoulders.
If left untreated, it can lead to serious problems like heart disease, diabetes, bone fractures, and severe infections. With timely treatment, the outlook is generally good and life expectancy is normal.
An endocrinologist is the main specialist for Cushing syndrome. In some cases, a neurosurgeon or general surgeon is also needed for tumor removal.
Cushing syndrome is rare in Pakistan. However, cases linked to long-term, unsupervised use of steroid medicines are more frequent because steroids are sometimes used without proper prescription. This makes it important to take such medicines only under medical advice.