Amclav is a combination antibiotic used for the treatment of bacterial infections. Amclav contains amoxicillin and salt of clavulanic acid. It is prescribed for a short period of time in order to prevent the growth of antibiotic-resistant bacteria.
Manufactured by: Getz Pharma
Generic: Amoxicillin trihydrate and Clavulanate potassium
Drug class: Antibiotic
Product form: Film-coated Tablet
Mechanism of Action
Amoxicillin is a semi-synthetic antibiotic derived from the penicillin nucleus. It is a broad-spectrum antibiotic and has bactericidal effects on a wide range of gram-positive and gram-negative bacteria. Clavulanate potassium is a 𝛃-lactamase inhibitor that increases the spectrum of antibiotic activity by targeting the 𝛃-lactamase enzyme in amoxicillin-resistant organisms
Available strengths
- 375 g Tablet (250 mg Amoxicillin, 125 mg Clavulanate potassium)
- 625 g Tablet (500 mg Amoxicillin, 25 mg Clavulanate potassium)
- 1 g Tablet (875 mg Amoxicillin, 25 mg Clavulanate potassium)
What is Amclav Tablet Price in Pakistan?
Amclav tablet price ranges between 27-30 PKR per tablet. Amclav cost varies depending on the tablet’s strength and manufacturer.
What is Amclav Tablet Used for?
Amclav tablet uses include short-term treatment of bacterial infections such as;
- Upper Respiratory Tract Infection: Amclav is indicated for the treatment of upper respiratory tract infections such as tonsillitis, otitis media, pharyngitis, and sinusitis. Higher doses of Amclav are prescribed for a short period of time to treat these infections.
- Lower Respiratory Tract Infections: Amclav in high doses is prescribed for infections of the lower respiratory tract including pneumonia and bronchitis.
- Genito-urinary Infections: Bacterial infections affecting the genitals and urinary tract are treated by Amclav. These include infection of the female genitals and urethritis.
- Skin Infections: Lower doses of Amclav are prescribed for the treatment of various skin infections caused by bacteria. Amclav is also indicated for treating infections of skin structure and soft tissues like cellulitis, abscess, boils, etc.
- Bones Infection: Amclav uses include the treatment of infections affecting the bones and joints.
- Sepsis: Amclav treats the life-threatening sepsis caused due to body’s extreme response to an infection. Gastrointestinal, lungs, and urinary infections usually result in sepsis. Amclav treats these infections by imparting bactericidal effects on the causative bacteria.
- Prophylaxis of Infection: Amclav is used for the prophylaxis of post-operative infections. It is indicated after all major surgeries like joint replacement surgery, cardiac surgery, gastric surgery, and biliary surgery.
Also Read: Amoxicillin tablet uses
How to take Amclav?
Follow the given recommendations while on Amclav;
- Amclav or Co-Amoxiclav tablet is taken orally with water.
- Take the tablet as a whole.
- Do not crush or chew the tablet.
- Do not discontinue the medicine on your own even if the symptoms disappear. Complete the entire course of Amclav antibiotic as prescribed.
- Amclav is only indicated for short-term use. Avoid using the medicine for the treatment of infections it is not prescribed for.
- Amclav can result in serious allergic reactions. Discontinue the medicine and inform the doctor immediately if symptoms of allergy appear.
- Avoid taking the medicine until at least 4 hours after the previous dose.
What is the Amclav Tablet dosage?
Amclav dosage depends on the severity of the infection it is treating and the age of the patient.
The usual recommended adult dose prescribed for Amclav is;
- For mild to moderate infections: One tablet of 375 mg three times a day OR 625 mg three two times a day
- For severe infections: 1-2 g Amclav three times a day
For children, Amclav tablet dosage depends on body weight.
Consult a doctor immediately for an Amclav antibiotic prescription based on the site and extent of infections.
What are Amclav Tablet’s side effects?
Some of the side effects reported due to Amclav antibiotic are;
- Diarrhea
- Nausea and vomiting
- Abdominal pain
Rare side effects are;
- Pruritis
- Urticaria
- Jaundice (Particularly due to long-term treatment with Amclav)
- Mild teeth discoloration
If any of these side effects worsen, discontinue the medicine and inform the doctor immediately.
What are the warnings and precautions associated with Amclav Tablet?
The warnings and precautions for using Amclav antibiotic are;
- Amclav is contraindicated in patients with penicillin allergy.
- Avoid using Amclav in patients with a history of jaundice or hepatic issues due to the use of Amclav, previously.
- Prolonged use of this antibiotic can result in the development of resistant bacteria and bacterial overgrowth.
- Dose adjustment is required for patients with renal and hepatic impairments.
- Amclav is not indicated for the treatment of infections in children under 12 years of age.
- The dose is adjusted for children above 12 years based on their body weight.
- Amclav can affect the blood cell count. Careful monitoring is required during the therapy to prevent complications.
Read Also: Azomax capsule uses and price in Pakistan
Does Amclav Tablet react with medicines?
Amclav antibiotic can show drug-drug interactions with a few medicines including;
- Probenecid
- Allopurinol
- Warfarin
Inform your doctor about all the OTC, herbal, and prescription medicines that you are taking to avoid complications associated with drug interactions.
Is Amclav Tablet safe during Pregnancy?
Amclav is assigned pregnancy category- B by FDA as it has shown no teratogenic effects in animal studies. As a safety precaution, Amclav should only be used on prescription when its benefits outclass the probable risks.
Trace amounts of Amclav are secreted in breast milk. Hence, it should be used with caution in lactating women.
Consult with a gynecologist before using Amclav antibiotics in pregnancy or while breastfeeding.
What are the alternatives to Amclav Tablet?
Some of the available alternatives to the Amclav tablet in Pakistan are;
- Augmentin
- Clavamox
- Auget
What happens with an Amclav Tablet Overdose?
Always follow the prescribed dose and the dosing schedule of antibiotics. Do not exceed the maximum recommended dose of Amclav. Intentional or accidental overdose can cause;
- Dark colored urine
- Blood in urine
- Fainting
- Yellowing of skin
Report the drug overdose immediately to the doctor to avoid any life-threatening situation.
What happens if you miss the Amclav Tablet?
Take the antibiotics strictly as per the prescription. If you miss the dose, take it as soon as you remember. If the time of the next dose is near, skip the missed dose and take the scheduled dose. Take the next dose of Amclav no less than 4 hours after the previous dose.
How to store Amclav Tablet?
The instructions to store the Amclav tablet are;
- Store the medicine at 25 ℃.
- Keep the medicine in a dry place
- Protect Amclav tablet from direct sunlight
- Keep all medicines out of the reach of children.
Consult a doctor immediately if you need a prescription for using the Amclav tablet.
FAQs
1. What is the use of the Amclav 1g tablet?
Amclav 1 g is indicated for the short-term treatment of severe bacterial infections. It is used for the treatment of upper and lower respiratory tract infections, skin infections, and sepsis.
2. How many days can you take Amoxiclav?
Amoxiclav is usually recommended for use, not more than 3 days due to its increased ability to develop antibiotic resistance in bacteria. Exceeding the prescribed dosing schedule of Amoxiclav can also result in bacterial overgrowth.
3. Is Amoxiclav a good antibiotic?
Amclav is a broad-spectrum antibiotic with an additional ability of 𝛃-lactamase inhibition in bacteria resistant to amoxicillin alone. It is a good antibiotic used for a short time to treat severe bacterial infections.
