Book Video Consultation
Stay Home
No Waiting in lines
Audio/Video Call
PMC Verified Doctors
Asking for Self, Male, 36 years old, Bahawalpur
Respected Sir, My younger brother having a mass in Ascending colon and colonoscopy done.on biopsy poorly differentiated adenocarcinoma of colon.then Rt extended Hemicolectomy done. Chemo therapy starts with Injection Avestin Inj CPT and Inj 5FU.9 cycles done in september 2018.through out chemo courses CEA leavel was with in range .now in April he felt pain in Abdomen and CT scan done .report of CT scan showing left Para aortic Lymphadenopathy. after that we did PET can from Inmol. Pet scan conclusion is. Metabolically Active Nodal disease in Abdomen consistent with viable metastatic disease .FDG AVID Multiple sites in transverse colona and splenic flexure, Neoplastic ? now BINO (Atomic energy hospital Bahawalpur Started Chemo again with ERBITUX 640 stat and 400 mg weekly Inj irinitcan 280 mg and inj 5FU please guide me what should i do continue this or should go towards surgery.. Regards
Please send me pathology report including mutation analysis ,kras ,egfr etc. Thanks
Why FOLFOX ( Oxaliplatin + 5Fu ) was not given initially. Was it metastatic disease at the time of diagnosis. Another question is that why Avastin was used initially. Recent PET Scan revealed metastatic disease. Is this the 1st PET or it was also done before, and if done before, what was the findings at that time. Regarding re-surgery, it will not be helpful at this stage.
Patient
Post Owner
Thanks for your reply. Initially 3 out of 21 lymphy nodes involved.yes it is 1st PET scan .please tell me the prognosis
5 years ago
surgery is not possible at this stage due to extensive disease. did BINO doctor check KRAS mutation before prescribing ERBITUX?? if not then it should be done if mutation is wild type then ERBITUX is not indicated. I think XELIRI chemo is better option
you initial treatment is not started as per protocol
Patient
Post Owner
Thanks for reply. KRAS was wild type.now ERBITUX 400mg given weekly with FOLFOX+5fu fortnightly. please recommend me can i go for cyberknife.if surgery is not possible,7 cycle of erbitux400 mg(7 weeks) given .please need your opinion.
Regards
95 Positive Reviews