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Asking for Other, Male, 45 years old, Hyderabad
Aik doc han unky pass 1 patient aya he was congo virus patient jo k bd m pta chala test k bd 2 din wh consaltant usy check krty rhy to kya wh consaltant bhi effect h sakty hn want 2 know symptoms of congo virus .he just touch his wrist and talk 2 him pz help my friend is very upset about his brother
Assalamoalaikum,
Jee, possibility hai k wo effect hon...mgr zaroori nhi. Baqi wo khud doctor hain tou symptoms pr nazr rkh lein ge.
U CAN READ INTO DETAIL. The Crimean-Congo haemorrhagic fever virus in animals and ticks
The hosts of the CCHF virus include a wide range of wild and domestic animals such as cattle, sheep and goats. Many birds are resistant to infection, but ostriches are susceptible and may show a high prevalence of infection in endemic areas, where they have been at the origin of human cases. For example, a former outbreak occurred at an ostrich abattoir in South Africa. There is no apparent disease in these animals.
Animals become infected by the bite of infected ticks and the virus remains in their bloodstream for about one week after infection, allowing the tick-animal-tick cycle to continue when another tick bites. Although a number of tick genera are capable of becoming infected with CCHF virus, ticks of the genus Hyalomma are the principal vector.
Transmission
The CCHF virus is transmitted to people either by tick bites or through contact with infected animal blood or tissues during and immediately after slaughter. The majority of cases have occurred in people involved in the livestock industry, such as agricultural workers, slaughterhouse workers and veterinarians.
Human-to-human transmission can occur resulting from close contact with the blood, secretions, organs or other bodily fluids of infected persons. Hospital-acquired infections can also occur due to improper sterilization of medical equipment, reuse of needles and contamination of medical supplies.
Signs and symptoms
The length of the incubation period depends on the mode of acquisition of the virus. Following infection by a tick bite, the incubation period is usually one to three days, with a maximum of nine days. The incubation period following contact with infected blood or tissues is usually five to six days, with a documented maximum of 13 days.
Onset of symptoms is sudden, with fever, myalgia, (muscle ache), dizziness, neck pain and stiffness, backache, headache, sore eyes and photophobia (sensitivity to light). There may be nausea, vomiting, diarrhoea, abdominal pain and sore throat early on, followed by sharp mood swings and confusion. After two to four days, the agitation may be replaced by sleepiness, depression and lassitude, and the abdominal pain may localize to the upper right quadrant, with detectable hepatomegaly (liver enlargement).
Other clinical signs include tachycardia (fast heart rate), lymphadenopathy (enlarged lymph nodes), and a petechial rash (a rash caused by bleeding into the skin) on internal mucosal surfaces, such as in the mouth and throat, and on the skin. The petechiae may give way to larger rashes called ecchymoses, and other haemorrhagic phenomena. There is usually evidence of hepatitis, and severely ill patients may experience rapid kidney deterioration, sudden liver failure or pulmonary failure after the fifth day of illness.
The mortality rate from CCHF is approximately 30%, with death occurring in the second week of illness. In patients who recover, improvement generally begins on the ninth or tenth day after the onset of illness.
Diagnosis
CCHF virus infection can be diagnosed by several different laboratory tests:
enzyme-linked immunosorbent assay (ELISA) ;
antigen detection;
serum neutralization;
reverse transcriptase polymerase chain reaction (RT-PCR) assay; and
virus isolation by cell culture.
Patients with fatal disease, as well as in patients in the first few days of illness, do not usually develop a measurable antibody response and so diagnosis in these individuals is achieved by virus or RNA detection in blood or tissue samples.
Tests on patient samples present an extreme biohazard risk and should only be conducted under maximum biological containment conditions. However, if samples have been inactivated (e.g. with virucides, gamma rays, formaldehyde, heat, etc.), they can be manipulated in a basic biosafety environment.
We have personal Experiance of treating CCHF at JPMC. Generally chances of these low risk exposure to cause disease is very low though cannot be excluded. Symptoms post exposure are fever, nuasea and bodyache to begin with. Monitor fever with thermometer for 15 days. If fever occur send CCHF PCR.
Risk of transmission is realistic if someone have been taking care of critically ill patients with so many body fluid exposure like vomitus, URINE, blood or alive.
Causal touch or hand shake in Vitally stable ambulatory patient rarely have human to human transmission.
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